Genome Instability at The Lewis Katz School of Medicine, Philadelphia, PA

Come by and meet our Midatlantic Sales Rep, Kevin Gattie! There will be free samples and promotional items for you to grab! 

If you would like to contact Kevin before the show, please see his contact information below:  

Phone: (201) – 247 – 0021  

Email: Keving@celltreat.com 

FREE – Genome Instability: Discovery to Personalized Medicine
November 21, 2025
Philadelphia, PA
7:30 – 8:15 BREAKFAST
8:20 – 8:30 INTRODUCTION: Tomasz Skorski, Amy Goldberg, Josh Gladden, Johnathan Chernoff
8:30 – 10:15 SESSION 1: Mechanisms of DNA damage repair
Chair: Robin Sebastian
8:30 – 9:00 – Neil Johnson: The BRCA1-PALB2 axis in DNA repair and cancer
9:00 – 9:30 – Karen Vasquez: Distinct Mechanisms of Genetic Instability Induced by Alternative (non-B)
DNA Structures
9:30 – 10:00 –Georgios Karras: Protein Folding Vulnerabilities in DNA Repair
10:00 – 10:15 – selected short talk 1 –
10:15 – 10:45 – COFFEE BREAK
10:45 – 12:30 SESSION 2: New strategies in personalized medicine
Chair: Sergey Karakashew & Michael Soniat
10:45 – 11:15 – Richard Pomerantz: Inhibition of Polq polymerase potentiates PARP inhibitors in BRCAmutant
xenograft models
11:15 – 11:45 – Michele Pagano: G1 Cyclins Control Mismatch Repair Dynamics
11:45 – 12:15 – Carman Li: Toward a Better Understanding of Hereditary Cancer: Dissecting BRCA1
Haploinsufficiency Through Precise In Vivo Models
12:15 – 12:30 – selected short talk 2 –
12:30 – 1:45 – LUNCH
1:45 – 3:30 SESSION 3: Novel translational approaches
Chair: Sara Small
1:45 – 2:15 – Laurie Sanders: Precision-based medicine approaches for Parkinson’s disease
2:15 – 2:45 –Jaroslaw Maciejewski: Somatic gene rescue: a general evolutionary principle of
leukemogenesis
2:45 – 3:15 – Priyanka Verma: Exploiting cancer cell intrinsic vulnerabilities to design new therapeutic
strategies
3:15 – 3:30 – selected short talk 3 –
3:30 – 3:45 – COFFEE BREAK
3:45 – 4:30 – KEYNOTE SPEAKER:
Chair: Tomasz Skorski
Andre Nussenzweig: Maintaining genome stability in mitotic and post-mitotic cells
4:30 – 5:30 – POSTER SESSION/DRINKS + APPETIZERS