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SUMMARY:Genome Instability at The Lewis Katz School of Medicine\, Philadelphia\, PA
DESCRIPTION:Come by and meet our Midatlantic Sales Rep\, Kevin Gattie! There will be free samples and promotional items for you to grab!  \nIf you would like to contact Kevin before the show\, please see his contact information below:   \nPhone: (201) – 247 – 0021   \nEmail: Keving@celltreat.com  \nFREE – Genome Instability: Discovery to Personalized Medicine\nNovember 21\, 2025\nPhiladelphia\, PA\n7:30 – 8:15 BREAKFAST\n8:20 – 8:30 INTRODUCTION: Tomasz Skorski\, Amy Goldberg\, Josh Gladden\, Johnathan Chernoff\n8:30 – 10:15 SESSION 1: Mechanisms of DNA damage repair\nChair: Robin Sebastian\n8:30 – 9:00 – Neil Johnson: The BRCA1-PALB2 axis in DNA repair and cancer\n9:00 – 9:30 – Karen Vasquez: Distinct Mechanisms of Genetic Instability Induced by Alternative (non-B)\nDNA Structures\n9:30 – 10:00 –Georgios Karras: Protein Folding Vulnerabilities in DNA Repair\n10:00 – 10:15 – selected short talk 1 –\n10:15 – 10:45 – COFFEE BREAK\n10:45 – 12:30 SESSION 2: New strategies in personalized medicine\nChair: Sergey Karakashew & Michael Soniat\n10:45 – 11:15 – Richard Pomerantz: Inhibition of Polq polymerase potentiates PARP inhibitors in BRCAmutant\nxenograft models\n11:15 – 11:45 – Michele Pagano: G1 Cyclins Control Mismatch Repair Dynamics\n11:45 – 12:15 – Carman Li: Toward a Better Understanding of Hereditary Cancer: Dissecting BRCA1\nHaploinsufficiency Through Precise In Vivo Models\n12:15 – 12:30 – selected short talk 2 –\n12:30 – 1:45 – LUNCH\n1:45 – 3:30 SESSION 3: Novel translational approaches\nChair: Sara Small\n1:45 – 2:15 – Laurie Sanders: Precision-based medicine approaches for Parkinson’s disease\n2:15 – 2:45 –Jaroslaw Maciejewski: Somatic gene rescue: a general evolutionary principle of\nleukemogenesis\n2:45 – 3:15 – Priyanka Verma: Exploiting cancer cell intrinsic vulnerabilities to design new therapeutic\nstrategies\n3:15 – 3:30 – selected short talk 3 –\n3:30 – 3:45 – COFFEE BREAK\n3:45 – 4:30 – KEYNOTE SPEAKER:\nChair: Tomasz Skorski\nAndre Nussenzweig: Maintaining genome stability in mitotic and post-mitotic cells\n4:30 – 5:30 – POSTER SESSION/DRINKS + APPETIZERS
URL:https://www.celltreat.com/event/genome-instability-at-the-lewis-katz-school-of-medicine-philadelphia-pa/
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