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CELLTREAT 3D Cell Culture
CELLTREAT® Scientific Products has partnered with 3D Biotek, LLC to manufacture and supply multi-well cell culture plates with 3D Inserts, a series of 3D scaffolds for three dimensional cell and tissue culture. CELLTREATR 3D Cell Culture Plates are available containing either Polystyrene or Polycaprolactone inserts.
Benefits of 3D Cell Culture:
- Mimic in vivo cellular environments more accurately with 3D cell growth
- Reduce animal testing
- Yield more predictive data from in vitro study
- Improve cell culture efficiency
- Increase the production yield of cytokines, antibodies, and other biological molecules
- Greater stem cell differentiation
- Reduce cost and time to identify new drug candidates
- Reduce time to market
Click here for a variety of technical information on CELLTREATR 3D Cell Culture.
3d insert PCL Cell Culture Plate" title="3d insert PCL Cell Culture Plate
human fibroblasts
3d insert PS Cell Culture Plate
3D InsertTM-PS Cell Culture Plates :
3D InsertTM-PS Scaffolds are ideal for daily 3D cell culture applications. By utilizing our 3D InsertTM-PS you can turn an ordinary 2D monolayer cell culture into a novel 3 dimensional cell culture environment, enhancing routine cell culture, drug discovery, cancer models and stem cell differentiation.
Pre-Sterilized and Ready to Use
Our 3D InsertTM-PS scaffolds are prepackaged into wells of tissue culture plates and sterilized using γ-radiation. PS Scaffolds are available in prepackaged tissue culture plates ranging from 6-well to 96-well plates.
100% Connectivity
The pores of the products are 100% open, making it easy for cells to be seeded throughout the porous scaffolds and the nutrient and cell metabolic waste to be exchanged. This feature makes the products especially useful in conducting dynamic cultures where the medium can perfuse through the 100% open porous structure.
Well Defined Pore Size and Porous Structure
The precision microfabrication technology produces a well-defined pore size and ensures the reproducibility of the porous structure from batch to batch.
Easy Monitoring Cell Growth
3D InsertTM-PS scaffolds are made from polystyrene, the same material as the traditional tissue culture plates. The combination of transparency of the material and the porous structure design makes it possible to monitoring cell growth under an inverted light microscope.
Mechanically Strong and Easy to Handle
3D InsertTM-PS scaffolds are mechanically strong. Therefore, they are easy to handle and manipulate when needed.
Free of Animal Derived Material
Our PS Scaffolds are made from 100% synthetic polymer with consistent quality to ensure experimental reproducibility when using different batches of 3D InsertTM-PS.
Improved Cell Culture Efficiency
3D cell culture products have increased surface areas as compared to 2D cell culture plates. Therefore more cells can be cultured using the same size cell culture dish/plates/flasks/bioreactors.
Easy Separation of Cytokines and Growth Factors Secreted by Cultured Cells
Our 3D cell culture scaffolds will not absorb cytokines and growth factors. Therefore, cytokines and growth factors, which are secreted by cultured cells during 3D culture, can be easily separated or recovered from the culture medium without going through any extra separation steps.
Compatible with Most 2D Cell Culture Protocols, Including Trypsin Digestion Protocol
Cells cultured in non-degradable scaffolds can be assayed using most 2D cell culture assay protocols. Cultured cells can be easily harvested using the same trypsin digestion protocol as in the 2D cell culture.
3D Cell Culture Evaluation Plates:
| Celltreat Part Number | Description | 3D InsertTM Type | Fiber Diameter | Fiber Spacing | Suggested List Price (USD) |
|---|---|---|---|---|---|
| 212041520 | 12-well sterile 3D cell culture plate with 4-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $58 |
| 296121520 | 96-well sterile 3D cell culture plate with 12-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $58 |
3D Cell Culture Research Plates:
| Celltreat Part Number | Description | 3D InsertTM Type | Fiber Diameter | Fiber Spacing | Suggested List Price (USD) |
|---|---|---|---|---|---|
| 206031520 | 6-well sterile 3D cell culture plate with 3-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $106 |
| 206033040 | 6-well sterile 3D cell culture plate with 3-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜300µm | ˜400µm | $106 |
| 212061520 | 12-well sterile 3D cell culture plate with 6-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $106 |
| 212063040 | 12-well sterile 3D cell culture plate with 6-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜300µm | ˜400µm | $106 |
| 224121520 | 24-well sterile 3D cell culture plate with 12-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $106 |
| 224123040 | 24-well sterile 3D cell culture plate with 12-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜300µm | ˜400µm | $106 |
| 296241520 | 96-well sterile 3D cell culture plate with 24-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜150µm | ˜200µm | $106 |
| 296243040 | 96-well sterile 3D cell culture plate with 24-3D non-degradable polymer (Polystyrene) scaffolds | PS | ˜300µm | ˜400µm | $106 |
3D InsertTM-PCL Cell Culture Plates
Polycaprolactone (PCL) is a biodegradable polymer used in many FDA approved implants, drug delivery devices, sutures, as well as for a wide variety of applications in tissue engineering research. These applications include:
- Bone/Cartilage
- Cardiovascular
- Nerve
- Skin
- Tendon/Ligament
- Liver
Pre-Sterilized and Ready to Use
3D InsertTM-PCL scaffolds are prepackaged into wells of tissue culture plates and terminally sterilized using γ-radiation. Currently our PCL Scaffolds are available in prepackaged tissue culture plates ranging from 6-well to 96-well plates.
100% Connectivity
The pores of the products are 100% open, making it easy for cells to be seeded throughout the porous scaffolds and the nutrient and cell metabolic waste to be exchanged. This feature makes the products especially useful in conducting dynamic cultures where the medium can perfuse through the 100% open porous structure.
Well Defined Pore Size and Porous Structure
3D InsertTM-PCL scaffolds precision microfabrication technology produces a well-defined pore size and ensures the reproducibility of the porous structure from batch to batch.
Improved Cell Culture Efficiency
3D InsertTM-PCL scaffolds have increased surface areas as compared to 2D cell culture plates. There, more cells can be cultured using the same size cell culture dish/plates/flasks/bioreactors.
Easy Separation of Cytokines and Growth Factors Secreted by Cultured Cells
Our 3D cell culture scaffolds will not absorb cytokines and growth factors. Therefore, cytokines and growth factors, which are secreted by cultured cells during 3D culture, can be easily separated or recovered from the culture medium without going through any extra separation steps.
Organic Solvent Free
Cytotoxic organic solvents, such as chloroform and methylene chloride, are often used in fabricating PCL scaffolds. 3D Biotek's precision micro-fabrication technology is a solvent-free manufacturing process. Therefore, the 3D InsertTM- PCL is free of organic solvent.
3D Cell Culture Evaluation Plates:
| Celltreat Part Number | Description | 3D InsertTM Type | Fiber Diameter | Fiber Spacing | Suggested List Price (USD) |
|---|---|---|---|---|---|
| 312043030 | 12-well sterile 3D cell culture plate with 4-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $108 |
| 396123030 | 96-well sterile 3D cell culture plate with 12-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $108 |
3D Cell Culture Research Plates:
| Celltreat Part Number | Description | 3D InsertTM Type | Fiber Diameter | Fiber Spacing | Suggested List Price (USD) |
|---|---|---|---|---|---|
| 306033030 | 6-well sterile 3D cell culture plate with 3-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $215 |
| 306033050 | 6-well sterile 3D cell culture plate with 3-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜500µm | $215 |
| 312063030 | 12-well sterile 3D cell culture plate with 6-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $215 |
| 312063050 | 12-well sterile 3D cell culture plate with 6-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜500µm | $215 |
| 324123030 | 24-well sterile 3D cell culture plate with 12-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $215 |
| 324123050 | 24-well sterile 3D cell culture plate with 12-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜500µm | $215 |
| 396243030 | 96-well sterile 3D cell culture plate with 24-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜300µm | $215 |
| 396243050 | 96-well sterile 3D cell culture plate with 24-3D polycaprolactone (PCL) scaffolds | PCL | ˜300µm | ˜500µm | $215 |
